Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | NQO2 | P16083 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317972 | 0.84 | HTR2A (0.67) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL23023138 | 0.84 | HTR2A (0.86) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL31332137 | 0.84 | HTR2A (0.86) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL827963 | 0.83 | HTR2A (0.70) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL8148735 | 0.83 | AKR1B1 (0.65) | MTNR1AMTNR1BHTR2AAKR1B1 | |
| SCHEMBL1882845 | 0.81 | HTR2A (0.68) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL29594789 | 0.81 | HTR2A (0.68) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL14714813 | 0.81 | HTR2A (0.68) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL17444606 | 0.81 | HTR2A (0.68) | MTNR1AMTNR1BHTR2ANQO2HTR2C | |
| SCHEMBL124465 | 0.81 | HTR2A (0.68) | MTNR1AMTNR1BHTR2ANQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012208-A1 | PROCESS FOR THE MANUFACTURE OF AGOMELATINE AND ITS INTERMEDIATE | 江苏恩华药业股份有限公司 (CN) | 2010-02-04 | — | — | WO | disclosed |