SCHEMBL3248731

SCHEMBL3248731

CN(C)c1ccc(C=CC23OCCN2c2ccc(Cl)cc2C3(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 6/20 0.39
▸ MAPT P10636 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ INSR P06213 1/20 0.35
▸ BCHE P06276 1/20 0.34
▸ KDM4E B2RXH2 3/20 0.33
▸ GAA P10253 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ SLC2A1 P11166 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ RELA Q04206 1/20 0.31
▸ ALDH3A1 P30838 1/20 0.31
▸ ALDH1A3 P47895 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12311091 1.00 APP (0.39) APPMAPTMEN1KMT2ANPC1
SCHEMBL3251936 1.00 APP (0.39) APPMAPTMEN1KMT2ANPC1
SCHEMBL3255181 0.94 APP (0.37) APPMAPTMEN1KMT2ANPC1
SCHEMBL3242468 0.94 APP (0.37) APPMAPTMEN1KMT2ANPC1
SCHEMBL13963628 0.94 APP (0.38) APPMAPTMEN1KMT2ANPC1
SCHEMBL3253087 0.89 APP (0.37) APPMAPTMEN1KMT2ANPC1
SCHEMBL3247245 0.89 APP (0.37) APPMAPTMEN1KMT2ANPC1
SCHEMBL3248594 0.88 APP (0.41) APPMAPTBCHEKDM4EGAA
SCHEMBL13846603 0.88 BCHE (0.34) APPMAPTMEN1KMT2ANPC1
SCHEMBL3248597 0.88 APP (0.41) APPMAPTBCHEKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747774-B1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres OREAL (FR) 2010-05-05 — — EP claimed
US-7585332-B2 Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device L'OREAL S.A. (FR) 2009-09-08 — — US claimed
EP-2083790-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'Oreal (FR) 2009-08-05 — — EP claimed
EP-2083923-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'Oreal (FR) 2009-08-05 — — EP claimed
US-7399319-B2 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2008-07-15 — — US claimed
WO-2008043967-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'OREAL (FR) 2008-04-17 — — WO claimed
WO-2008043968-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'OREAL (FR) 2008-04-17 — — WO claimed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US claimed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP claimed
US-8437067-B2 Electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-05-07 — — US disclosed
US-20110019265-A1 DISPLAY ELEMENT AND METHOD OF FORMING POROUS LAYER IN DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-27 — — US disclosed
US-20110013261-A1 ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-20 — — US disclosed
WO-2010128214-A1 TREATMENT OF COLORED FIBERS BY STYRYL OR IMINE COMPOUNDS IN THE PRESENCE OF ORGANIC OR INORGANIC ACIDS AND ZINC SALTS L´OREAL (FR) 2010-11-11 — — WO disclosed
EP-2083923-B1 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE OREAL (FR) 2010-05-05 — — EP disclosed
US-20080189878-A1 Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process L'OREAL S.A. (FR) 2008-08-14 — — US disclosed
US-7399319-B2 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2008-07-15 — — US disclosed
WO-2008043967-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'OREAL (FR) 2008-04-17 — — WO disclosed
WO-2008043968-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'OREAL (FR) 2008-04-17 — — WO disclosed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US disclosed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080189878-A1 Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process KRT18, INHA, IK APP 1105/4885MAPT 854/4885MEN1 2999/4885
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers KRT18, INHA, IK APP 1682/4885MAPT 1182/4885MEN1 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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