Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254812 | 0.89 | MEN1 (0.42) | MEN1KMT2ARCE1RXFP1KDM4E | |
| SCHEMBL3251453 | 0.88 | RXFP1 (0.43) | MEN1KMT2ARXFP1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL3247796 | 0.84 | KDM4E (0.41) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL3252092 | 0.82 | KMT2A (0.50) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL3249354 | 0.81 | KDM4E (0.45) | MEN1KMT2ARXFP1KDM4EGAA | |
| SCHEMBL3247885 | 0.81 | BRD4 (0.44) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL3248851 | 0.80 | KDM4E (0.38) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL3251597 | 0.79 | PARG (0.47) | KDM4EALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL3255160 | 0.78 | MAPT (0.38) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL4160299 | 0.78 | MEN1 (0.42) | MEN1KMT2ARXFP1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |