Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247242 | 1.00 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL3247244 | 1.00 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3251786 | 0.99 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3247550 | 0.99 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3247555 | 0.99 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL4818815 | 0.89 | GAA (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL3249121 | 0.86 | KDM4E (0.39) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL3253488 | 0.86 | KDM4E (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL3250390 | 0.86 | KDM4E (0.37) | GAAKDM4EHTTHSD17B10HPGD | |
| SCHEMBL3250387 | 0.86 | KDM4E (0.37) | GAAKDM4EHTTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | disclosed |