Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247232 | 0.91 | HRH3 (0.76) | HRH3CYP2D6 | |
| SCHEMBL3249806 | 0.89 | HRH3 (0.76) | HRH3CYP2D6 | |
| SCHEMBL3241070 | 0.89 | HRH3 (0.79) | HRH3CYP2D6 | |
| SCHEMBL3247580 | 0.88 | HRH3 (0.62) | HRH3CYP2D6 | |
| SCHEMBL3243602 | 0.87 | HRH3 (0.76) | HRH3CYP2D6 | |
| SCHEMBL3240547 | 0.85 | HRH3 (0.74) | HRH3CYP2D6 | |
| SCHEMBL1379627 | 0.85 | HRH3 (1.00) | HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL3248065 | 0.85 | HRH3 (0.76) | HRH3CYP2D6 | |
| SCHEMBL1552607 | 0.85 | HRH3 (0.76) | HRH3CYP2D6 | |
| SCHEMBL3247637 | 0.84 | HRH3 (0.73) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118089-B1 | INDOL-2-YL-PIPERAZIN-1-YL-METHANONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-05-12 | — | — | EP | claimed |