⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13988143 | 0.82 | — | — | |
| SCHEMBL26148308 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29607808 | 0.79 | — | — | |
| Iodide SCHEMBL19118626 | 0.78 | — | — | |
| Biguanide SCHEMBL27995971 | 0.78 | — | — | |
| Pimagedine SCHEMBL3818920 | 0.78 | — | — | |
| SCHEMBL14433093 | 0.77 | — | — | |
| SCHEMBL27630221 | 0.76 | — | — | |
| SCHEMBL8658374 | 0.75 | — | — | |
| Pimagedine SCHEMBL15307 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12010996-B2 | Tris-substituted biguanide compounds and their uses | CHEN HWANG HSING (US) | 2024-06-18 | — | — | US | claimed |
| US-20220015366-A1 | TRIS-SUBSTITUTED BIGUANIDE COMPOUNDS AND THEIR USES | CHEN HWANG HSING (US) | 2022-01-20 | — | — | US | claimed |
| EP-3876737-A1 | TRIS-SUBSTITUTED BIGUANIDE COMPOUNDS AND THEIR USES | Chen, Hwang-Hsing (US) | 2021-09-15 | — | — | EP | claimed |
| CN-113056199-A | Trisubstituted biguanide compounds and uses thereof | 陈煌兴 | 2021-06-29 | — | — | CN | claimed |
| US-11044912-B2 | Branched polymeric biguanide compounds and their uses | CHEN HWANG HSING (US) | 2021-06-29 | — | — | US | claimed |
| CN-107961231-B | Cream for improving diabetic skin complications and preparation method thereof | 上海交通大学医学院附属瑞金医院 | 2020-06-05 | — | — | CN | claimed |
| US-20190373895-A1 | BRANCHED POLYMERIC BIGUANIDE COMPOUNDS AND THEIR USES | CHEN HWANG HSING (US) | 2019-12-12 | — | — | US | claimed |
| CN-110121548-A | Branched polymeric biguanide compound and application thereof | 陈煌兴 | 2019-08-13 | — | — | CN | claimed |
| CN-108853556-A | A kind of contact lens,hard care composition and preparation method thereof containing sodium lactate | 欧普康视科技股份有限公司 | 2018-11-23 | — | — | CN | claimed |
| WO-2018128823-A1 | BRANCHED POLYMERIC BIGUANIDE COMPOUNDS AND THEIR USES | CHEN HWANG HSING (US) | 2018-07-12 | — | — | WO | claimed |
| CN-101391111-A | Contact lens care solution or moisturizing eye lotion containing polyoxyethylene hydrogenated castor oil | GUANGZHOU CONMASTER EYEGLASS C (CN) | 2009-03-25 | — | — | CN | claimed |
| JP-2009509922-A | — | — | 2009-03-12 | — | — | JP | claimed |
| EP-1940773-A2 | POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS | Johns Hopkins University (US) | 2008-07-09 | — | — | EP | claimed |
| US-20070255004-A1 | ANTISEPTIC CONTAINING SILICONE ELASTOMERS | BAYER BUSINESS SERVICES GMBH (DE) | 2007-11-01 | — | — | US | claimed |
| US-20070208082-A1 | POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS | JOHN HOPKINS UNIVERSITY (US) | 2007-09-06 | — | — | US | claimed |
| WO-2007021839-A2 | POLYAMINES USEFUL AS ANTI-PARASITIC AND ANTI-CANCER THERAPEUTICS AND AS LYSINE-SPECIFIC DEMETHYLASE INHIBITORS | JOHNS HOPKINS UNIVERSITY (US) | 2007-02-22 | — | — | WO | claimed |
| EP-1455804-A4 | USE OF NANOPARTICLES AS CARRIERS FOR BIOCIDES IN OPHTHALMIC COMPOSITIONS | ALCON INC (CH) | 2005-01-05 | — | — | EP | claimed |
| US-20040241206-A1 | Use of nanoparticles as carriers for biocides in ophthalmic compositions | ALCON INC. (CH) | 2004-12-02 | — | — | US | claimed |
| EP-1455804-A2 | USE OF NANOPARTICLES AS CARRIERS FOR BIOCIDES IN OPHTHALMIC COMPOSITIONS | Alcon Inc. (CH) | 2004-09-15 | — | — | EP | claimed |
| WO-2003059193-A2 | USE OF NANOPARTICLES AS CARRIERS FOR BIOCIDES IN OPHTHALMIC COMPOSITIONS | ALCON, INC. (CH) | 2003-07-24 | — | — | WO | claimed |