SCHEMBL325385

SCHEMBL325385

N#CC1CCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937488 1.00
SCHEMBL2223474 1.00
Hydrochloric Acid SCHEMBL222471 0.97
Hydrochloric Acid SCHEMBL222472 0.97
Hydrochloric Acid SCHEMBL222662 0.97
Hydrochloric Acid SCHEMBL18547503 0.95
SCHEMBL1019673 0.84
SCHEMBL13632296 0.84
SCHEMBL12259738 0.84
SCHEMBL102903 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261213-B1 FGFR INHIBITOR COMPOUND AND USE THEREOF SHENZHEN KANGSU PHARMACEUTICAL TECH CO LTD (CN) 2026-04-15 EP claimed
EP-4071145-B1 JAK INHIBITOR COMPOUND AND USE THEREOF LU LIANG (CN) 2025-01-08 EP claimed
EP-4472739-A1 IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2024-12-11 EP claimed
CN-114981270-B MLL1 inhibitors and anticancer agents 诺华公司 2024-10-18 CN claimed
EP-3886845-B1 NOVEL SUBSTITUTED PIPERAZINE AMIDE COMPOUNDS AS INDOLEAMINE 2, 3-DIOXYGENASE (IDO) INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-09-04 EP claimed
CN-114127057-B Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof 德西费拉制药有限责任公司 2024-07-12 CN claimed
CN-118284602-A Pyridine derivatives as sodium channel activators and uses thereof 泽农医药公司 2024-07-02 CN claimed
CN-114222744-B Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFNα response 百时美施贵宝公司 2024-06-25 CN claimed
EP-4013756-B1 MLL1 INHIBITORS AND ANTI-CANCER AGENTS NOVARTIS AG (CH) 2024-05-08 EP claimed
EP-3822273-B1 SUBSTITUTED TRICYCLIC COMPOUNDS AS FGFR INHIBITORS INCYTE HOLDINGS CORP (US) 2024-04-10 EP claimed
CN-105008362-B Pyrrolo [2,3-D ] pyrimidine derivatives as janus-related kinase (JAK) inhibitors 辉瑞大药厂 2017-06-06 CN claimed
CN-106459035-A N2-phenyl-pyrido[3,4-d]pyrimidine-2,8-diamine derivatives and their use as mps1 inhibitors 癌症研究科技有限公司 2017-02-22 CN claimed
EP-2576541-A1 AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS F.HOFFMANN-LA ROCHE AG (CH) 2013-04-10 EP claimed
EP-2501691-A1 SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES F. Hoffmann-La Roche AG (CH) 2012-09-26 EP claimed
WO-2011151360-A1 AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2011-12-08 WO claimed
WO-2011073277-A1 PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 WO claimed
WO-2011061139-A1 SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES F. HOFFMANN-LA ROCHE AG (CH) 2011-05-26 WO claimed
CN-101993404-A Method for synthesizing N-Boc-3-pyrrolidine formaldehyde ZHANPENG LIU 2011-03-30 CN claimed
WO-1995001962-A1 PROCESS FOR THE PREPARATION OF CHIRAL 3-(1-AMINO-1,1-BISALKYLMETHYL)-1-SUBSTITUTED-PYRROLIDINES WARNER-LAMBERT COMPANY (US) 1995-01-19 WO claimed
US-5347017-A Process for chiral 3-(1-amino-1,1-bisalkylmethyl)-1-substituted-pyrrolidines WARNER-LAMBERT COMPANY (US) 1994-09-13 US claimed