Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13058564 | 1.00 | PTGDR2 (0.38) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13058559 | 1.00 | PTGDR2 (0.38) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13058563 | 0.89 | PTGDR2 (0.37) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10238180 | 0.83 | PTGDR2 (0.39) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13058569 | 0.77 | MEN1 (0.34) | PTGDR2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL609497 | 0.72 | PTGDR2 (0.39) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13058567 | 0.71 | KDM4E (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL3252041 | 0.70 | HRH3 (0.39) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13058481 | 0.70 | HRH3 (0.39) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3749201 | 0.69 | HRH3 (0.38) | PTGDR2ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188294-B1 | TRICYCLIC BRIDGED CYCLOPENTANEDIONE DERIVATIVES AS HERBICIDES | SYNGENTA LTD (GB) | 2015-03-18 | — | — | EP | disclosed |
| US-8530667-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20100298140-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | US | disclosed |
| EP-2188294-A2 | TRICYCLIC BRIDGED CYCLOPENTANEDIONE DERIVATIVES AS HERBICIDES | Syngenta Limited (GB) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009030450-A2 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298140-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | PTGDR2 2873/4885ALDH1A1 10/4885CYP1A2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.