Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.59 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258276 | 1.00 | NPC1 (0.70) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| SCHEMBL15339502 | 0.88 | NPC1 (0.65) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| Confusoside SCHEMBL30870423 | 0.85 | NPC1 (0.73) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| Confusoside SCHEMBL31296555 | 0.85 | NPC1 (0.73) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| Confusoside SCHEMBL28640287 | 0.85 | NPC1 (0.73) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| SCHEMBL1734687 | 0.81 | NPC1 (0.52) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| SCHEMBL30870414 | 0.79 | SLC5A1 (0.73) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| SCHEMBL28346617 | 0.79 | NPC1 (0.74) | NPC1RAB9ASLC5A1SLC28A3KDM4E | |
| SCHEMBL1734591 | 0.77 | NPC1 (0.46) | NPC1RAB9ASLC5A1SLC5A2HPGD | |
| SCHEMBL4948839 | 0.77 | MEN1 (0.55) | NPC1RAB9ASLC5A1SLC5A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715761-B2 | Flavor molecules | GIVAUDAN S.A. (CH) | 2014-05-06 | — | — | US | disclosed |
| US-8449936-B2 | Flavor molecules | GIVAUDAN SA (CH) | 2013-05-28 | — | — | US | disclosed |
| US-20100040753-A1 | FLAVOR MOLECULES | GIVAUDAN SA (CH) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040753-A1 | FLAVOR MOLECULES | TAS2R30, TAS2R31, TAS2R1 | NPC1 3284/4885RAB9A 1700/4885SLC5A1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.