Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174089 | 0.82 | SCN3A (0.64) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3163597 | 0.81 | SCN3A (0.66) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3167975 | 0.80 | SCN3A (0.59) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3154182 | 0.80 | SCN3A (0.61) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3169627 | 0.78 | SCN3A (0.59) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3168731 | 0.78 | SCN3A (0.62) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL12010898 | 0.78 | MAPT (0.80) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3168130 | 0.78 | SCN3A (0.64) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3174028 | 0.78 | SCN3A (0.63) | SCN3AMAPTMEN1KMT2ALMNA | |
| SCHEMBL3163302 | 0.77 | SCN3A (0.71) | SCN3AMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995241-B1 | Inhibitors of ion channels | ICAGEN INC (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1995241-A1 | Inhibitors of ion channels | ICAgen, Incorporated (US) | 2008-11-26 | — | — | EP | disclosed |