Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL29354220 | 0.80 | HSPA5 (0.37) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL8530620 | 0.73 | SRC (0.38) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| Phosphoric Acid SCHEMBL30363099 | 0.73 | SMN1; SMN2 (0.40) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL9192461 | 0.73 | SMN1; SMN2 (0.40) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL4201014 | 0.72 | SMN1; SMN2 (0.39) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL3163229 | 0.71 | SMN1; SMN2 (0.38) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL28378334 | 0.70 | SMN1; SMN2 (0.37) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| Pyrophosphoric Acid SCHEMBL30494703 | 0.69 | NR5A2 (0.32) | — | |
| SCHEMBL5181891 | 0.68 | BTN3A1 (0.34) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A | |
| SCHEMBL1537344 | 0.68 | HSPA5 (0.36) | HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2163577-B9 | Chain-extenders and foamed thermoplastic cellular materials obtained by reactive extrusion process and with help of said chain-extenders | ARMACELL ENTERPRISE GMBH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2163577-B1 | Chain-extenders and foamed thermoplastic cellular materials obtained by reactive extrusion process and with help of said chain-extenders | ARMACELL ENTERPRISE GMBH (DE) | 2012-08-15 | — | — | EP | disclosed |
| EP-2163577-A1 | Foamed thermoplastic cellular materials obtained by reactive extrusion process and with help of chain-extenders | Armacell Enterprise GmbH (DE) | 2010-03-17 | — | — | EP | disclosed |