Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 12/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034579 | 0.94 | HMGCR (0.46) | HMGCR | |
| SCHEMBL3162906 | 0.94 | HMGCR (0.44) | HMGCR | |
| SCHEMBL2050591 | 0.94 | HMGCR (0.46) | HMGCR | |
| SCHEMBL3167877 | 0.93 | HMGCR (0.47) | HMGCR | |
| SCHEMBL3964715 | 0.93 | HMGCR (0.47) | HMGCR | |
| Methylamine SCHEMBL3171804 | 0.92 | HMGCR (0.46) | HMGCR | |
| SCHEMBL3259413 | 0.86 | HMGCR (0.56) | HMGCR | |
| SCHEMBL13100382 | 0.86 | HMGCR (0.56) | HMGCR | |
| SCHEMBL16568794 | 0.86 | HMGCR (0.44) | HMGCR | |
| SCHEMBL17073105 | 0.85 | HMGCR (0.46) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902036-B1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN AND INTERMEDIATES | RICHTER GEDEON NYRT (HU) | 2010-03-24 | — | — | EP | disclosed |