SCHEMBL3259733

SCHEMBL3259733

NC(=S)c1cc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5591159 0.98
SCHEMBL6208530 0.81
SCHEMBL1273778 0.80
SCHEMBL4961404 0.78
SCHEMBL19150296 0.76
SCHEMBL7561905 0.76
SCHEMBL28761094 0.76
SCHEMBL1274 0.76
SCHEMBL525584 0.76
Bromide SCHEMBL21598344 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925630-B Preparation method of pyrazole thioamide 金仓(上海)医药生物科技有限公司 2025-03-25 CN claimed
CN-115925630-A Preparation method of pyrazole thioamide 金仓(上海)医药生物科技有限公司 2023-04-07 CN claimed
EP-1966146-A1 4,5-DIHYDRO- (1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS Solvay Pharmaceuticals B.V. (NL) 2008-09-10 EP claimed
WO-2007071662-A1 4,5-DIHYDRO- (1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS SOLVAY PHARMACEUTICALS B.V. (NL) 2007-06-28 WO claimed
US-7173055-B1 Pyrazolecarboxamide and pyrazolethioamide as fungicide SYNGENTA CROP PROTECTION, INC. (US) 2007-02-06 US claimed
WO-2007009688-A1 THIOCARBONYL-SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 MODULATORS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-01-25 WO claimed
EP-0942904-B1 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2004-06-23 EP claimed
US-6518296-B1 For controlling at least one pest selected from the group consisting of insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2003-02-11 US claimed
CN-1311780-A Substituted 3-thiocarbamoylpyrazoles BAYER AG (DE) 2001-09-05 CN claimed
US-6265430-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-07-24 US claimed
US-20010007876-A1 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-07-12 US claimed
EP-1084111-A1 SUBSTITUTED 3-THIOCARBAMOYLPYRAZOLES Bayer Aktiengesellschaft (DE) 2001-03-21 EP claimed
CN-1239953-A 3-thiocarbamoylpyrazole derivatives as pesticides BAYER AG (DE) 1999-12-29 CN claimed
WO-1999062886-A1 SUBSTITUTED 3-THIOCARBAMOYLPYRAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1999-12-09 WO claimed
US-12534440-B2 Compounds with copper- or zinc-activated toxicity against microbial infection KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2026-01-27 US disclosed
US-12534440-B2 Compounds with copper- or zinc-activated toxicity against microbial infection KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2026-01-27 US disclosed
CN-115925630-B Preparation method of pyrazole thioamide 金仓(上海)医药生物科技有限公司 2025-03-25 CN disclosed
EP-0638556-A1 Medicaments containing 1-Thiocarbamoyl-5-hydroxy pyrazoles and their use as agents for the treatment of septic shock BAYER AG (DE) 1995-02-15 EP disclosed
EP-0151866-B1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES ELI LILLY AND COMPANY (US) 1990-07-25 EP disclosed
EP-0151866-A2 Herbicidal pyrazole-(thio)-carboxamides ELI LILLY AND COMPANY (US) 1985-08-21 EP disclosed