SCHEMBL3260343

SCHEMBL3260343

OC[C@@H]1O[C@H]1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 6/20 0.50
CYP2C19 P33261 4/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
MAPT P10636 1/20 0.42
EPHX1 P07099 2/20 0.41
PTGS2 P35354 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3191462 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9475305 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9486651 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL1535687 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9475300 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9486645 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9543216 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL9543039 1.00 SLC5A2 (0.50) SLC5A2CYP2C19CYP3A4CYP2D6MAPT
SCHEMBL4139162 0.83 SLC5A2 (0.71) SLC5A2
SCHEMBL20529512 0.83 SLC5A2 (0.71) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2056445-A None JP disclosed
US-11043336-B2 Actinic and electron beam radiation curable water based electrode binders and electrodes incorporating same MILTEC CORPORATION (US) 2021-06-22 US disclosed
US-10544133-B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2020-01-28 US disclosed
EP-2997612-B1 ACTINIC AND ELECTRON BEAM RADIATION CURABLE WATER BASED ELECTRODE BINDERS AND ELECTRODES INCORPORATING SAME MILTEC CORP (US) 2019-11-20 EP disclosed
US-20190019631-A1 Actinic and Electron Beam Radiation Curable Water Based Electrode Binders and Electrodes Incorporating Same MILTEC CORPORATION 2019-01-17 US disclosed
US-20180370956-A1 HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS BRISTOL MYERS SQUIBB CO (US) 2018-12-27 US disclosed
US-10102979-B2 Actinic and electron beam radiation curable water based electrode binders and electrodes incorporating same MILTEC CORPORATION (US) 2018-10-16 US disclosed
US-10023562-B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-07-17 US disclosed
US-20170210730-A1 HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS BRISTOL MYERS SQUIBB CO (US) 2017-07-27 US disclosed
US-9657009-B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2017-05-23 US disclosed
WO-2000048593-A1 EPOXIDE HYDROLASE COMPLEXES AND METHODS THEREWITH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-08-24 WO disclosed
US-5391735-A Process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane FARMITALIA CARLO ERBA S.P.A. (IT) 1995-02-21 US disclosed
US-5250572-A Treating depression ELI LILLY AND COMPANY (US) 1993-10-05 US disclosed
EP-0301401-B1 LEUKOTRIENE ANTAGONISTS, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE TREATMENT OF ILLNESSES HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-27 EP disclosed
US-5068433-A Antidepressants FARMITALIA CARLO ERBA, S.R.L. (IT) 1991-11-26 US disclosed
US-4937331-A Chemical intermediates for antibiotics PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1990-06-26 US disclosed
JP-H0256445-A PRODUCTION OF (R)-ALPHA-METHOXYPHENYLACETIC ACID TOOA EIYOO KK 1990-02-26 JP disclosed
EP-0334593-A1 Chiral azetidinone epoxides THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1989-09-27 EP disclosed
US-4851440-A ASTHMA HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed
EP-0301401-A2 Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544133-B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators IRAK4, IRAK3, IRAK2 SLC5A2 4393/4885CYP2C19 3316/4885CYP3A4 1228/4885
US-10023562-B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators IRAK4, IRAK3, IRAK2 SLC5A2 4393/4885CYP2C19 3316/4885CYP3A4 1228/4885
US-20180370956-A1 HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS IRAK4, IRAK3, IRAK2 SLC5A2 4393/4885CYP2C19 3316/4885CYP3A4 1228/4885
US-20170210730-A1 HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS IRAK4, IRAK3, IRAK2 SLC5A2 4393/4885CYP2C19 3316/4885CYP3A4 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.