Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778655 | 1.00 | HCRTR1 (0.44) | HCRTR1HCRTR2PRCPGRM5KDM4E | |
| SCHEMBL2777098 | 0.93 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2776668 | 0.88 | PRCP (0.41) | HCRTR1HCRTR2PRCPHTR2B | |
| SCHEMBL2778773 | 0.86 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL1836139 | 0.86 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL2777502 | 0.85 | PRCP (0.46) | PRCP | |
| SCHEMBL9605169 | 0.83 | USP30 (0.51) | HCRTR1HCRTR2HTR2B | |
| SCHEMBL2779204 | 0.83 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2775522 | 0.82 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL2777787 | 0.82 | HCRTR1 (0.46) | HCRTR1HCRTR2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017401-A1 | BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-11 | — | — | WO | claimed |