Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 11/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835617 | 0.89 | SMO (0.70) | SMO | |
| SCHEMBL28899685 | 0.82 | SMO (0.76) | SMO | |
| SCHEMBL3261532 | 0.82 | SMO (1.00) | SMO | |
| SCHEMBL3206860 | 0.82 | SMO (1.00) | SMO | |
| SCHEMBL28899656 | 0.82 | SMO (0.85) | SMO | |
| SCHEMBL28899672 | 0.82 | SMO (0.69) | SMO | |
| SCHEMBL3215871 | 0.81 | SMO (0.68) | SMO | |
| SCHEMBL13534433 | 0.80 | SMO (0.87) | SMO | |
| SCHEMBL13534030 | 0.80 | SMO (1.00) | SMO | |
| SCHEMBL28899640 | 0.79 | SMO (0.81) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318389-B1 | PYRIDAZINE DERIVATIVES AS SMO INHIBITORS | NOVARTIS AG (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2010007120-A1 | PYRIDAZINE DERIVATIVES AS SMO INHIBITORS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |