Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236257 | 0.84 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3260690 | 0.82 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL3239951 | 0.82 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL3234862 | 0.82 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL3232558 | 0.80 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL3236855 | 0.80 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3263130 | 0.78 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL2371367 | 0.78 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3235989 | 0.78 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CGAK | |
| SCHEMBL3236840 | 0.77 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029299-A1 | PYRIMIDINONE DERIVATIES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |