Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 4/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.35 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457704 | 1.00 | PTPN11 (0.43) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6422373 | 0.87 | PTPN11 (0.59) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3196604 | 0.87 | PTPN11 (0.59) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3260942 | 0.78 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL6421561 | 0.71 | PTPN11 (0.55) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3195027 | 0.71 | PTPN11 (0.55) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8922483 | 0.71 | PTPN11 (0.55) | PTPN11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3184382 | 0.71 | PTPN11 (0.55) | PTPN11IDO1ALDH1A1LTB4R2 | |
| SCHEMBL18664391 | 0.71 | KDM4E (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7167541 | 0.71 | RARB (0.54) | PTPN11PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7682521-B2 | Aligned liquid crystal thin films and glasses | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-03-23 | — | — | US | disclosed |
| US-20070080322-A1 | Aligned liquid crystal thin films and glasses | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2007-04-12 | — | — | US | disclosed |
| WO-2005019911-A2 | ALIGNED LIQUID CRYSTAL THIN FILMS AND GLASSES | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2005-03-03 | — | — | WO | disclosed |