Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.68 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802751 | 0.96 | S1PR1 (0.68) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL7029045 | 0.95 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL27602528 | 0.95 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL27959074 | 0.95 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL28663946 | 0.95 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL27959059 | 0.95 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL24799744 | 0.94 | S1PR1 (0.68) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| SCHEMBL7029673 | 0.94 | S1PR1 (0.61) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| Hydrochloric Acid SCHEMBL10335558 | 0.93 | S1PR1 (0.69) | S1PR1S1PR3S1PR5S1PR4CHRNB2 | |
| Fluoride SCHEMBL29251951 | 0.93 | S1PR1 (0.60) | S1PR1S1PR3S1PR5S1PR4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100178333-A1 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2010-07-15 | — | — | US | disclosed |
| EP-1976487-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | Astron Research Limited (IN) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007086079-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |