Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224875 | 0.94 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3263016 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3227713 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3238589 | 0.90 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3238726 | 0.87 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3264711 | 0.87 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3234652 | 0.85 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3262194 | 0.85 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3238567 | 0.85 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3265583 | 0.85 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029299-A1 | PYRIMIDINONE DERIVATIES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |