Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798303 | 0.95 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL2798402 | 0.91 | HRH3 (0.92) | HRH3KCNH2 | |
| SCHEMBL24433453 | 0.88 | HRH3 (0.86) | HRH3KCNH2 | |
| SCHEMBL2798033 | 0.84 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL3262377 | 0.83 | HRH3 (0.86) | HRH3KCNH2 | |
| SCHEMBL2798245 | 0.83 | HRH3 (0.97) | HRH3KCNH2 | |
| SCHEMBL2795653 | 0.78 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL2799920 | 0.78 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL16600284 | 0.78 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL3264740 | 0.77 | HRH3 (0.91) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162452-A1 | SPIROCYCLOPROPYL PIPERIDINE DERIVATIVES | AstraZeneca AB (SE) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008147314-A1 | SPIROCYCLOPROPYL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-12-04 | — | — | WO | disclosed |