⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263080 | 1.00 | — | — | |
| Water SCHEMBL28215428 | 0.98 | OR51E2 (0.40) | — | |
| SCHEMBL27671313 | 0.95 | OR51E2 (0.33) | — | |
| SCHEMBL27881462 | 0.83 | MAPT (0.34) | — | |
| SCHEMBL11155839 | 0.82 | CYP3A4 (0.35) | — | |
| SCHEMBL11158578 | 0.82 | CYP3A4 (0.31) | — | |
| SCHEMBL27546132 | 0.81 | CYP3A4 (0.32) | — | |
| SCHEMBL16561370 | 0.78 | — | — | |
| SCHEMBL169398 | 0.78 | — | — | |
| SCHEMBL11403455 | 0.78 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046361-A1 | AZEPINE FUSED RING COMPOUND AS RIPK1 INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2024-03-07 | — | — | WO | disclosed |
| CN-116617154-A | High-efficiency transdermal delivery system for acidic group-containing biological materials | 浙江大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116617407-A | High-permeability protein or polypeptide conjugate and application thereof | 浙江大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116135877-A | Polymer-insulin conjugate containing tertiary amine oxide group with high permeability | 浙江大学 | 2023-05-19 | — | — | CN | disclosed |
| CN-114369358-B | Cellulose-containing resin composition | 旭化成株式会社 | 2022-11-11 | — | — | CN | disclosed |
| CN-114369358-A | Cellulose-containing resin composition | 旭化成株式会社 | 2022-04-19 | — | — | CN | disclosed |
| CN-111971491-A | Gear containing cellulose | 旭化成株式会社 | 2020-11-20 | — | — | CN | disclosed |
| US-7771802-B2 | Optical compensation film, polarizing plate and liquid crystal display apparatus | FUJIFILM CORPORATION (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20070292680-A1 | Optical film, production method of optical film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2007-12-20 | — | — | US | disclosed |
| US-20070132925-A1 | Optical compensation film, polarizing plate and liquid crystal display apparatus | FUJIFILM CORPORATION (JP) | 2007-06-14 | — | — | US | disclosed |
| US-5767099-A | CONTAINING LIPOPHILIC GROUPS DERIVED FROM STEROIDS | GENZYME CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |