Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472444 | 0.84 | NPC1 (0.57) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL2744415 | 0.82 | NPC1 (0.59) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL9567802 | 0.80 | NPC1 (0.55) | NPC1RAB9ALMNAALDH1A1CYP3A4 | |
| SCHEMBL6028192 | 0.80 | NPC1 (0.56) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL29354035 | 0.80 | NPC1 (0.46) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL29903 | 0.80 | NPC1 (0.46) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL29384618 | 0.80 | KDM4E (0.42) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL5081275 | 0.80 | KDM4E (0.42) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL20272359 | 0.79 | NPC1 (0.41) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL29904482 | 0.79 | NPC1 (0.41) | NPC1RAB9ALMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167573-A2 | UV BARRIER FILM | Innovia Films Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009013529-A2 | UV BARRIER FILM | INNOVIA FILMS LIMITED (GB) | 2009-01-29 | — | — | WO | disclosed |