Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199667 | 0.88 | PDE4A (0.54) | PDE4APDE4DPDE4BPDE4CPTAFR | |
| SCHEMBL1157236 | 0.87 | PDE4A (0.58) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157778 | 0.85 | PDE4A (0.57) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4832392 | 0.84 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157791 | 0.84 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157365 | 0.84 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157497 | 0.83 | PDE4A (0.62) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157534 | 0.83 | PDE4A (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157768 | 0.82 | PDE4A (0.58) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1158003 | 0.82 | PDE4A (0.61) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | claimed |
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |