Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104709 | 0.88 | RCE1 (0.42) | RCE1P4HTMLDHALDHBNR1H4 | |
| SCHEMBL3111814 | 0.78 | GCG (0.47) | — | |
| SCHEMBL3090561 | 0.77 | GCG (0.36) | RCE1LDHALDHBPRKAA2CHEK1 | |
| SCHEMBL3091283 | 0.77 | RCE1 (0.41) | RCE1NR1H4 | |
| SCHEMBL3109922 | 0.74 | RCE1 (0.52) | RCE1LDHALDHBKDM4EKMT2A | |
| SCHEMBL3100198 | 0.72 | RCE1 (0.47) | RCE1KMT2AMAPT | |
| SCHEMBL718060 | 0.72 | P4HTM (0.40) | RCE1P4HTMNR1H4KDM4EGLA | |
| SCHEMBL3101297 | 0.71 | RCE1 (0.41) | RCE1 | |
| SCHEMBL3102340 | 0.71 | GCGR (0.51) | — | |
| SCHEMBL3090387 | 0.71 | RCE1 (0.46) | RCE1KDM4EKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210876-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-07-28 | — | — | EP | disclosed |