Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263844 | 0.90 | MAPT (0.82) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3262032 | 0.86 | MAPT (1.00) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3264281 | 0.86 | MAPT (0.83) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3218859 | 0.85 | MAPT (0.81) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3216521 | 0.83 | MAPT (0.78) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3226019 | 0.80 | MAPT (1.00) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3215772 | 0.78 | MAPT (0.80) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL13534780 | 0.78 | MAPT (0.68) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3260219 | 0.77 | MAPT (0.71) | MAPTPOLBALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL3219024 | 0.77 | MAPT (0.68) | MAPTPOLBALDH1A1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003197-A1 | MORPHOLINE DERIVATIVES USED AS ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | WO | claimed |