Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135345 | 0.70 | CHRM3 (0.35) | — | |
| SCHEMBL10785589 | 0.70 | — | — | |
| SCHEMBL22368 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL28139107 | 0.68 | HPGD (0.40) | MAPTKMT2A | |
| SCHEMBL28043109 | 0.65 | ELANE (0.43) | MAPT | |
| Methylene Chloride SCHEMBL27870524 | 0.65 | — | — | |
| SCHEMBL28043107 | 0.64 | AKT1 (0.33) | — | |
| SCHEMBL28102271 | 0.64 | — | — | |
| SCHEMBL10596969 | 0.64 | KCNN4 (0.62) | CES1KCNN4NR1H2NR1H3MAPT | |
| SCHEMBL4517127 | 0.63 | MAPT (0.50) | CES1KCNN4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |