⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157374 | 0.65 | — | — | |
| SCHEMBL10754207 | 0.65 | — | — | |
| SCHEMBL19745643 | 0.64 | — | — | |
| SCHEMBL10713168 | 0.64 | — | — | |
| SCHEMBL12957552 | 0.61 | — | — | |
| SCHEMBL3385577 | 0.61 | — | — | |
| SCHEMBL11417280 | 0.58 | — | — | |
| SCHEMBL1200617 | 0.58 | — | — | |
| SCHEMBL5883960 | 0.55 | — | — | |
| SCHEMBL27682010 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103278-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2022-12-21 | — | — | EP | disclosed |
| EP-2471797-B1 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS ETC. | BUCK INST FOR RES ON AGING (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2471797-A2 | 17-Desmethylrapamycin and analogues thereof, methods for their production and their use as immunosupressants, anticancer agents, antifungal agents etc. | Biotica Technology Limited (GB) | 2012-07-04 | — | — | EP | disclosed |
| US-7803808-B2 | Production of polyketides and other natural products | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20090253732-A1 | Production Of Polyketides And Other Natural Products | BIOTICA TECHNOLOGY LIMITED | 2009-10-08 | — | — | US | disclosed |
| EP-2029611-A2 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS ETC. | Biotica Technology Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-7452704-B2 | Dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-11-18 | — | — | US | disclosed |
| WO-2008002959-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |
| US-7115735-B2 | Dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060205045-A1 | Which produces N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH as coenzyme; biosynthesis | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| WO-2006016167-A2 | 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR RODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS, ETC. | BIOTICA TECHNOLOGY LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
| US-20050124040-A1 | Novel dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-06-09 | — | — | US | disclosed |
| EP-0677060-A1 | PEPTIDE INHIBITORS OF CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994015958-A2 | PEPTIDE INHIBITORS OF CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-21 | — | — | WO | disclosed |
| EP-0538399-A1 | CYCLIC CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000995-A1 | CYCLIC CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO. LTD. (JP) | 1992-01-23 | — | — | WO | disclosed |