SCHEMBL3266009

SCHEMBL3266009

CC1C(=O)[N]C(=O)C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16204346 0.65
SCHEMBL10846680 0.65
SCHEMBL14084133 0.61
SCHEMBL12670167 0.61
SCHEMBL6032804 0.59
SCHEMBL1034862 0.59
SCHEMBL3555788 0.59
SCHEMBL583681 0.58
SCHEMBL9754658 0.57
SCHEMBL3691291 0.56 ATM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5519138-A ANGIOTENSIN ANTAGONIST DR. KARL THOMAE GMBH (DE) 1996-05-21 US claimed
EP-0529253-A1 Phenylalkylderivatives, compounds containing them and process for their fabrication Dr. Karl Thomae GmbH (DE) 1993-03-03 EP claimed
EP-1517881-B1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-02 EP disclosed
US-7414064-B2 4-(3,3-dihalo-allyloxy) phenoxy alkyl derivatives SYNGENTA CROP PROTECTION, INC. (US) 2008-08-19 US disclosed
US-20070142445-A1 4-(3,3-Dihalo-Allyloxy) Phenoxy Alkyl Derivatives SYNGENTA CROP PROTECTION, INC. (US) 2007-06-21 US disclosed
EP-1517881-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES Syngenta Participations AG (CH) 2005-03-30 EP disclosed
WO-2004002943-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-08 WO disclosed
US-6168934-B1 EFFICIENT GLYCOSYLATION BY MIXING ACCEPTOR SACCHARIDE, DONOR MONOSACCHARIDE, ACTIVATING NUCLEOTIDE, ACTIVATED DONOR MONOSACCHARIDE REGENERATING SYSTEM, PYROPHOSPHATE SCAVENGER, AND GLYCOSYLTRANSFERASE IN AN AQUEOUS MEDIUM THE SCRIPPS RESEARCH INSTITUTE 2001-01-02 US disclosed
EP-0576592-B1 OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS SCRIPPS RESEARCH INST (US) 2000-05-31 EP disclosed
US-5759823-A MIXING IN AQUEOUS MEDIUM ACTIVATED DONOR MONOSACCHARIDE WITH ACCEPTOR SACCHARIDE IN PRESENCE OF GLYCOSYLTRANSFERASE, MAINTAINING TO GLYCOSYLATE ACCEPTOR SACCHARIDE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-02 US disclosed
US-5593887-A Oligosaccharide enzyme substrates and inhibitors: methods and compositions THE SCRIPPS RESEARCH INSTITUTE (US) 1997-01-14 US disclosed
US-5519138-A ANGIOTENSIN ANTAGONIST DR. KARL THOMAE GMBH (DE) 1996-05-21 US disclosed
EP-0576592-A4 OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS SCRIPPS RESEARCH INST (US) 1996-01-24 EP disclosed
US-5461143-A Oligosaccharide enzyme substrates and inhibitors: methods and compositions THE SCRIPPS RESEARCH INSTITUTE (US) 1995-10-24 US disclosed
EP-0576592-A1 OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-01-05 EP disclosed
EP-0529253-A1 Phenylalkylderivatives, compounds containing them and process for their fabrication Dr. Karl Thomae GmbH (DE) 1993-03-03 EP disclosed
WO-1992016640-A1 OLIGOSACCHARIDE ENZYME SUBSTRATES AND INHIBITORS: METHODS AND COMPOSITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1992-10-01 WO disclosed
US-4176231-A Process for preparing 3-exomethylenecepham sulfoxides LILLY INDUSTRIES LIMITED (GB) 1979-11-27 US disclosed
US-4065471-A N-(4-Amino-2-butynyl)imides STERLING DRUG INC. (US) 1977-12-27 US disclosed