SCHEMBL32660337

SCHEMBL32660337

O=C1CCC(c2cc(F)c(CCS(=O)(=O)O)nn2)C(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.40
DDB1 Q16531 17/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32660537 0.85 CRBN (0.41) CRBNDDB1
SCHEMBL32660532 0.83 CRBN (0.40) CRBNDDB1
SCHEMBL32660675 0.83 CRBN (0.41) CRBNDDB1
SCHEMBL31101547 0.81 DDB1 (0.45) CRBNDDB1
SCHEMBL31103281 0.81 CRBN (0.45) CRBNDDB1
SCHEMBL31103266 0.81 CRBN (0.45) CRBNDDB1
SCHEMBL32660445 0.81 CRBN (0.38) CRBNDDB1
SCHEMBL32660504 0.80 CRBN (0.39) CRBNDDB1
SCHEMBL32660517 0.79 CRBN (0.37) CRBNDDB1
SCHEMBL32660594 0.78 CRBN (0.45) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP disclosed