SCHEMBL32660422

SCHEMBL32660422

O=C1CCC(c2cc(CCS(=O)(=O)O)nnc2F)C(=O)N1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.38
DDB1 Q16531 15/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32660290 0.85 CRBN (0.36) CRBNDDB1
SCHEMBL32660643 0.83 CRBN (0.37) CRBNDDB1
SCHEMBL32660520 0.83 CRBN (0.40) CRBNDDB1
SCHEMBL32660350 0.82 CRBN (0.36) CRBNDDB1
SCHEMBL32660445 0.81 CRBN (0.38) CRBNDDB1
SCHEMBL31101022 0.80 CRBN (0.44) CRBNDDB1
SCHEMBL31099733 0.80 CRBN (0.43) CRBNDDB1
SCHEMBL31100801 0.80 CRBN (0.43) CRBNDDB1
SCHEMBL31100569 0.78 CRBN (0.40) CRBNDDB1
SCHEMBL32660496 0.77 CRBN (0.36) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP disclosed