Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32661304 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661395 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661137 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661256 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661177 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661410 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661319 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661282 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661409 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 | |
| SCHEMBL32661252 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HRH3SIGMAR1TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015323-A1 | PIPERIDINE COMPOUNDS | TELO THERAPEUTICS INC (US) | 2026-01-15 | — | — | US | claimed |
| US-20260015323-A1 | PIPERIDINE COMPOUNDS | TELO THERAPEUTICS INC (US) | 2026-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015323-A1 | PIPERIDINE COMPOUNDS | XPO1, NR0B1, NR2E1 | KDM4E 3383/4885ALDH1A1 1959/4885HRH3 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.