⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457089 | 0.83 | — | — | |
| SCHEMBL5057324 | 0.81 | — | — | |
| SCHEMBL2953096 | 0.80 | — | — | |
| SCHEMBL992012 | 0.76 | — | — | |
| SCHEMBL963229 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL26187546 | 0.69 | — | — | |
| SCHEMBL1061098 | 0.68 | — | — | |
| SCHEMBL252367 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL7858703 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL7262903 | 0.67 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048436-A1 | Methods of synthesizing chemically cleavable phosphoramidite linkers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-02-19 | — | — | US | claimed |
| EP-3362089-B1 | IMMUNOGENIC COMPOSITIONS AGAINST S. AUREUS | SANOFI PASTEUR (FR) | 2023-12-06 | — | — | EP | disclosed |
| EP-3296306-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2022-11-09 | — | — | EP | disclosed |
| EP-2816053-B1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO KK (JP) | 2021-03-24 | — | — | EP | disclosed |
| US-10772946-B2 | Immunogenic compositions against S. aureus | SANOFI PASTEUR (FR) | 2020-09-15 | — | — | US | disclosed |
| US-20180280491-A1 | IMMUNOGENIC COMPOSITIONS AGAINST S. AUREUS | SANOFI PASTEUR (FR) | 2018-10-04 | — | — | US | disclosed |
| EP-3296306-A1 | BASE-PROTECTED OLIGONUCLEOTIDE | AJINOMOTO CO., INC. (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2976351-B1 | LIPOHILLIC OLIGONUCLEOTIDE ANALOGS | MILTENYI BIOTEC GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |
| US-9803198-B2 | Lipohillic oligonucleotide analogs | MILTENYI BIOTEC, GMBH (DE) | 2017-10-31 | — | — | US | disclosed |
| US-9371353-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20130267697-A1 | OLIGONUCLEOTIDE WITH PROTECTED BASE | AJINOMOTO CO., INC. (JP) | 2013-10-10 | — | — | US | disclosed |
| EP-2144633-A2 | A SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | Segev Laboratories Limited (IL) | 2010-01-20 | — | — | EP | disclosed |
| US-20090048436-A1 | Methods of synthesizing chemically cleavable phosphoramidite linkers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-02-19 | — | — | US | disclosed |
| US-20090047712-A1 | Chemically cleavable phosphoramidite linkers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-02-19 | — | — | US | disclosed |
| WO-2008129548-A2 | A SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | SEGEV LABORATORIES LIMITED (IL) | 2008-10-30 | — | — | WO | disclosed |
| US-20080004234-A1 | System for delivering therapeutic agents into living cells and cells nuclei | SEGEV LABORATORIES LIMITED (IL) | 2008-01-03 | — | — | US | disclosed |
| US-20060160763-A1 | System for delivering therapeutic agents into living cells and cells nuclei | SEGEV LABORATORIES LIMITED (IL) | 2006-07-20 | — | — | US | disclosed |
| WO-2006010084-A2 | A SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELL NUCLEI | SEGEV LABORATORIES LIMITED (IL) | 2006-01-26 | — | — | WO | disclosed |
| EP-0691979-A1 | NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM | SANOFI (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022890-A1 | NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM | STERLING WINTHOP INC. (US) | 1994-10-13 | — | — | WO | disclosed |