⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31385017 | 0.97 | — | — | |
| SCHEMBL13892976 | 0.83 | QARS1 (0.36) | — | |
| SCHEMBL2275662 | 0.81 | — | — | |
| SCHEMBL18410484 | 0.81 | — | — | |
| SCHEMBL26893956 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3579781 | 0.78 | — | — | |
| SCHEMBL10100208 | 0.76 | — | — | |
| SCHEMBL10208353 | 0.76 | — | — | |
| SCHEMBL8224798 | 0.74 | EPHX2 (0.44) | — | |
| SCHEMBL20046301 | 0.74 | EPHX2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022132-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | TREELINE BIOSCIENCES INC (US) | 2026-01-22 | — | — | US | disclosed |