Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.57 |
| ▸ | AGXT | P21549 | 11/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL32665385 | 0.98 | IDO1 (0.58) | IDO1AGXTCYP3A4CA1CA2 | |
| SCHEMBL16743905 | 0.81 | CA1 (0.42) | IDO1AGXTCA1CA2CA9 | |
| SCHEMBL31530153 | 0.80 | MAOB (0.60) | CYP3A4 | |
| SCHEMBL25920600 | 0.80 | MAOB (0.60) | CYP3A4 | |
| SCHEMBL32665337 | 0.79 | CA1 (0.41) | CA1CA2CA9 | |
| SCHEMBL18507891 | 0.78 | CA1 (0.60) | CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL32665152 | 0.77 | IDO1 (0.53) | IDO1AGXTCYP3A4CA1CA2 | |
| SCHEMBL23665653 | 0.75 | TAAR1 (0.46) | CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL32665491 | 0.74 | CA1 (0.44) | CA1CA2CA9 | |
| SCHEMBL437710 | 0.73 | IDO1 (0.71) | IDO1AGXTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | IDO1 3227/4885AGXT 2603/4885CYP3A4 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.