Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346007 | 0.80 | CA12 (0.59) | ALDH1A1HPGDSMN1; SMN2KDM4ECA12 | |
| SCHEMBL9131982 | 0.77 | CA12 (0.56) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD | |
| SCHEMBL13205433 | 0.77 | PDK2 (0.47) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD | |
| SCHEMBL29447970 | 0.77 | PDK2 (0.47) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD | |
| SCHEMBL32665581 | 0.75 | PTGS1 (0.42) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD | |
| SCHEMBL15173317 | 0.75 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19454508 | 0.74 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD | |
| SCHEMBL16104655 | 0.73 | TAAR1 (0.42) | ALDH1A1HPGDSMN1; SMN2MAOBAOC3 | |
| SCHEMBL4847261 | 0.73 | NCEH1 (0.45) | ERN1ALDH1A1HPGDMAOBAOC3 | |
| SCHEMBL355413 | 0.73 | ESR1 (0.60) | HSP90AA1HSP90AB1ERN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | HSP90AA1 1275/4885HSP90AB1 814/4885ERN1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.