SCHEMBL32665671

SCHEMBL32665671

Cc1cc(CC#N)cc(C(N)=O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.43
PARP1 P09874 2/20 0.42
SLC7A5 Q01650 1/20 0.37
IDH1 O75874 1/20 0.37
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
KCNH2 Q12809 1/20 0.36
MAPK8 P45983 1/20 0.35
TPMT P51580 1/20 0.35
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
C1S P09871 1/20 0.34
PRSS3 P35030 1/20 0.34
TSHR P16473 1/20 0.34
DHODH Q02127 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ELANE P08246 1/20 0.32
CTSB P07858 2/20 0.32
PGK1 P00558 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214437 1.00 PARP10 (0.43) PARP10PARP1SLC7A5IDH1OPRM1
SCHEMBL29130789 0.84 TPMT (0.55) SLC7A5TPMTKDM4ECTSBHCAR1
SCHEMBL937483 0.80 SLC7A5 (0.55) SLC7A5TSHRKDM4ETDP1
SCHEMBL5898518 0.80 PARP10 (0.49) PARP10PARP1SLC7A5IDH1OPRM1
SCHEMBL4515297 0.78 PARP10 (0.47) PARP10PARP1SLC7A5IDH1TPMT
SCHEMBL5898517 0.78 PARP10 (0.47) PARP10PARP1SLC7A5IDH1OPRM1
SCHEMBL1823353 0.77 KDM4E (0.43) IDH1TSHRKDM4ETDP1CTSB
SCHEMBL2262582 0.77 KDM4E (0.43) TSHRKDM4ETDP1CTSBPGK1
SCHEMBL4562246 0.77 PARP10 (0.46) PARP10PARP1SLC7A5IDH1OPRM1
SCHEMBL30914608 0.77 PARP10 (0.46) PARP10PARP1SLC7A5IDH1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121378044-B Preparation method of 3-cyanomethyl-5-methylbenzamide 成都艾迪医药技术有限公司 2026-04-17 CN disclosed
CN-121378044-B Preparation method of 3-cyanomethyl-5-methylbenzamide 成都艾迪医药技术有限公司 2026-04-17 CN disclosed
CN-121378044-A Preparation method of 3-cyanomethyl-5-methylbenzamide 成都艾迪医药技术有限公司 2026-01-23 CN disclosed
CN-121378044-A Preparation method of 3-cyanomethyl-5-methylbenzamide 成都艾迪医药技术有限公司 2026-01-23 CN disclosed