Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.51 |
| ▸ | F10 | P00742 | 11/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 10/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822370 | 1.00 | F2 (0.51) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL21822277 | 0.92 | F10 (0.55) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25015989 | 0.91 | F2 (0.50) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL31689657 | 0.90 | F2 (0.48) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25015887 | 0.90 | ST14 (0.51) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25016626 | 0.90 | F2 (0.48) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25017940 | 0.89 | F2 (0.54) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25015836 | 0.89 | F2 (0.46) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25017815 | 0.89 | CCR9 (0.47) | F2PRSS1F10ST14PRSS2 | |
| SCHEMBL25017830 | 0.88 | GCGR (0.48) | F2PRSS1F10ST14PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-B1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE INC (US) | 2026-01-28 | — | — | EP | disclosed |