Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266672 | 1.00 | PTGDR2 (0.58) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3275553 | 0.87 | PTGDR2 (0.70) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3275549 | 0.87 | PTGDR2 (0.70) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3268396 | 0.84 | PTGDR2 (0.72) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3268392 | 0.84 | PTGDR2 (0.72) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2086842 | 0.83 | PTGDR2 (0.79) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2086840 | 0.83 | PTGDR2 (0.79) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3274557 | 0.80 | PTGDR2 (0.70) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3274553 | 0.80 | PTGDR2 (0.70) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2090192 | 0.79 | PTGDR2 (0.38) | PTGDR2ALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740171-B1 | INDOL-1-YL-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-09 | — | — | EP | disclosed |