Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.33 |
| ▸ | BCL2 | P10415 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667689 | 0.91 | GRM2 (0.36) | IDH1TP53MDM2SCN5ASCN10A | |
| SCHEMBL30851284 | 0.82 | SCN5A (0.48) | TP53MDM2BCL2L1SCN5ASCN10A | |
| SCHEMBL32667347 | 0.79 | SCN5A (0.45) | TP53MDM2BCL2L1SCN5ASCN10A | |
| SCHEMBL32667589 | 0.77 | BCL2L1 (0.38) | TP53MDM2BCL2L1BCL2PTGS1 | |
| SCHEMBL32667718 | 0.77 | BCL2L1 (0.38) | IDH1TP53MDM2BCL2L1BCL2 | |
| SCHEMBL32667388 | 0.77 | CHRNA4 (0.42) | BCL2L1 | |
| SCHEMBL32667356 | 0.77 | BCL2L1 (0.41) | BCL2L1KCNH2BCL2 | |
| SCHEMBL32667638 | 0.74 | BCL2L1 (0.40) | BCL2L1SCN5ASCN10ASCN2ABCL2 | |
| SCHEMBL32667349 | 0.74 | MAPK14 (0.43) | SCN5ASCN10ASCN9ASCN2APTGS1 | |
| SCHEMBL32667337 | 0.73 | BCL2L1 (0.38) | IDH1BCL2L1SCN5ASCN10ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028326-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | GLUETACS THERAPEUTICS SHANGHAI CO LTD (CN) | 2026-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028326-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | CDR2, CYC1, CLN6 | IDH1 4/4885TP53 1856/4885MDM2 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.