SCHEMBL32667670

SCHEMBL32667670

CC(=O)OCc1c(-c2nc(Cl)cn3nccc23)cccc1-n1ccc2cc(C3CC3)cc(F)c2c1=O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ BTK Q06187 20/20 0.52
▸ CD69 Q07108 1/20 0.47
▸ KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17923516 0.82 BTK (0.55) BTK
SCHEMBL32667469 0.81 BTK (0.45) BTKCD69KCNH2
SCHEMBL32667769 0.79 BTK (0.55) BTK
SCHEMBL17781555 0.77 BTK (0.50) BTK
SCHEMBL22476354 0.75 BTK (0.63) BTK
SCHEMBL17937554 0.74 BTK (0.46) BTK
SCHEMBL17781722 0.74 BTK (0.83) BTKCD69KCNH2
Hydrochloric Acid SCHEMBL32667684 0.72 BTK (0.57) BTKKCNH2
SCHEMBL32667798 0.72 BTK (0.52) BTKCD69KCNH2
SCHEMBL20359451 0.72 BTK (0.54) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028346-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 — — US disclosed
US-20260028345-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028345-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, TEC BTK 1/4885CD69 1018/4885KCNH2 3617/4885
US-20260028346-A1 BTK DEGRADER AND USE THEREOF BTK, SYK, LYN BTK 1/4885CD69 1284/4885KCNH2 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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