SCHEMBL32667946

SCHEMBL32667946

c1ccc2ncc(-c3cnc4ccccc4c3)cc2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 4/20 0.77
PDGFRA P16234 4/20 0.77
CYP2A6 P11509 1/20 0.71
BIRC5 O15392 1/20 0.69
PIK3CD O00329 2/20 0.67
PIK3CA P42336 2/20 0.67
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA9 Q16790 1/20 0.62
CYP1A2 P05177 1/20 0.61
MAP4K4 O95819 1/20 0.59
CSNK1G2 P78368 1/20 0.59
CLK4 Q9HAZ1 1/20 0.59
MKNK2 Q9HBH9 1/20 0.59
MAP4K5 Q9Y4K4 1/20 0.59
NISCH Q9Y2I1 1/20 0.58
PIK3CB P42338 1/20 0.56
MTOR P42345 1/20 0.56
PIK3CG P48736 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772360 1.00 PDGFRB (0.77) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL708999 0.93 PDGFRB (0.75) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL26829682 0.91 PDGFRB (0.72) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL29375510 0.91 PDGFRB (0.72) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL30323720 0.91 BIRC5 (0.77) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL24621829 0.91 PDGFRB (0.72) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL27631118 0.91 BIRC5 (0.77) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL12074709 0.89 PDGFRB (0.70) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL2346887 0.88 PDGFRB (1.00) PDGFRBPDGFRACYP2A6BIRC5PIK3CD
SCHEMBL29818168 0.88 PDGFRB (0.62) PDGFRBPDGFRACYP2A6BIRC5PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121426744-A 3,3' -Bi-aromatic heterocyclic methane derivative, efficient synthesis method and application 新疆大学 2026-01-30 CN disclosed