SCHEMBL32668313

SCHEMBL32668313

COc1cc(-n2ncc3c(=O)n(CC4(O)CCN(C(=O)c5ccc(F)cc5)CC4)cnc32)ccc1F

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17869433 1.00 USP7 (0.63) USP7
SCHEMBL32668428 0.91 USP7 (0.68) USP7
SCHEMBL17869204 0.91 USP7 (0.68) USP7
SCHEMBL17870174 0.89 USP7 (0.68) USP7
SCHEMBL17894884 0.89 USP7 (0.68) USP7
SCHEMBL32668446 0.89 USP7 (0.62) USP7
SCHEMBL17869615 0.89 USP7 (0.62) USP7
SCHEMBL19888832 0.89 USP7 (0.71) USP7
SCHEMBL17869195 0.89 USP7 (0.61) USP7
SCHEMBL30967245 0.89 USP7 (0.61) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed