SCHEMBL32668341

SCHEMBL32668341

O=C(c1ccc(F)cc1)N1CCC(O)(Cn2cnc3c(cnn3-c3cccc(OCc4cccnc4)c3)c2=O)CC1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 19/20 0.55
PKM P14618 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17869511 1.00 USP7 (0.55) USP7PKMSMN1; SMN2
SCHEMBL32668308 0.93 USP7 (0.56) USP7
SCHEMBL17869137 0.93 USP7 (0.56) USP7
SCHEMBL17869285 0.93 USP7 (0.59) USP7SMN1; SMN2
SCHEMBL17869494 0.90 USP7 (0.63) USP7
SCHEMBL32668467 0.89 USP7 (0.54) USP7
SCHEMBL17870311 0.89 USP7 (0.54) USP7
SCHEMBL23023641 0.88 USP7 (0.55) USP7
SCHEMBL32668577 0.88 USP7 (0.57) USP7SMN1; SMN2
SCHEMBL17869847 0.88 USP7 (0.57) USP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed