SCHEMBL32668372

SCHEMBL32668372

CN(C)C(=O)N1CCC(O)(Cn2cnc3c(cnn3-c3ccc(F)c(N4CCNCC4)c3)c2=O)CC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 19/20 0.53
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17870030 1.00 USP7 (0.53) USP7SMN1; SMN2
SCHEMBL17870206 0.91 USP7 (0.53) USP7SMN1; SMN2
SCHEMBL32668390 0.91 USP7 (0.53) USP7SMN1; SMN2
SCHEMBL17868971 0.90 USP7 (0.52) USP7SMN1; SMN2
SCHEMBL17894620 0.89 USP7 (0.57) USP7
SCHEMBL32668485 0.87 USP7 (0.58) USP7SMN1; SMN2
SCHEMBL17869841 0.87 USP7 (0.58) USP7SMN1; SMN2
SCHEMBL17894810 0.87 USP7 (0.58) USP7
SCHEMBL17869165 0.85 USP7 (0.53) USP7
SCHEMBL17870067 0.85 USP7 (0.69) USP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed