SCHEMBL32668375

SCHEMBL32668375

N#Cc1cccc(COc2ccc(-n3ncc4c(=O)n(CC5(O)CCN(C(=O)c6ccc(F)cc6)CC5)cnc43)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17869272 1.00 USP7 (0.57) USP7
SCHEMBL32668467 0.95 USP7 (0.54) USP7
SCHEMBL17870311 0.95 USP7 (0.54) USP7
SCHEMBL17869337 0.92 USP7 (0.61) USP7
SCHEMBL17870169 0.90 USP7 (0.64) USP7
SCHEMBL23047019 0.90 USP7 (0.60) USP7
SCHEMBL30967277 0.89 USP7 (0.54) USP7
SCHEMBL17869190 0.89 USP7 (0.54) USP7
SCHEMBL17869060 0.87 USP7 (0.55) USP7
SCHEMBL17869734 0.87 USP7 (0.61) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed