SCHEMBL32668404

SCHEMBL32668404

O=C(NCCO)c1cccc(-c2cccc(-n3ncc4c(=O)n(CC5(O)CCN(C(=O)C6CC6)CC5)cnc43)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17870161 1.00 USP7 (0.51) USP7
SCHEMBL17869753 0.95 USP7 (0.51) USP7
SCHEMBL32668392 0.95 USP7 (0.51) USP7
SCHEMBL32668403 0.91 USP7 (0.53) USP7
SCHEMBL17869826 0.91 USP7 (0.53) USP7
SCHEMBL17894761 0.87 USP7 (0.51) USP7
SCHEMBL32668419 0.87 USP7 (0.51) USP7
SCHEMBL17869920 0.87 USP7 (0.61) USP7
SCHEMBL32668524 0.87 USP7 (0.61) USP7
SCHEMBL17870382 0.86 USP7 (0.53) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed