SCHEMBL32668451

SCHEMBL32668451

O=C(c1ccc(-c2cccc(-n3ncc4c(=O)n(CC5(O)CCN(C(=O)C6CC6)CC5)cnc43)c2)cc1)N1CCCC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17869893 1.00 USP7 (0.54) USP7
SCHEMBL17869770 0.92 USP7 (0.59) USP7
SCHEMBL32668311 0.92 USP7 (0.56) USP7
SCHEMBL17870125 0.92 USP7 (0.56) USP7
SCHEMBL32668549 0.90 USP7 (0.56) USP7
SCHEMBL17894583 0.90 USP7 (0.56) USP7
SCHEMBL32668524 0.90 USP7 (0.61) USP7
SCHEMBL17869920 0.90 USP7 (0.61) USP7
SCHEMBL17894846 0.90 USP7 (0.56) USP7
SCHEMBL32668476 0.90 USP7 (0.56) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed