SCHEMBL32668481

SCHEMBL32668481

O=C(C1CC1)N1CCC(O)(Cn2cnc3c(cnn3-c3cccc(CN4CCC5(CCOCC5)C4)c3)c2=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 19/20 0.50
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17869425 1.00 USP7 (0.50) USP7LMNA
SCHEMBL17869252 0.92 USP7 (0.59) USP7
SCHEMBL32668395 0.92 USP7 (0.54) USP7LMNA
SCHEMBL17869671 0.92 USP7 (0.54) USP7LMNA
SCHEMBL17869439 0.89 USP7 (0.53) USP7LMNA
SCHEMBL32668439 0.89 USP7 (0.53) USP7LMNA
SCHEMBL17869897 0.88 USP7 (0.55) USP7
SCHEMBL32668406 0.88 USP7 (0.55) USP7
SCHEMBL17870020 0.87 USP7 (0.55) USP7
SCHEMBL32668422 0.87 USP7 (0.55) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed