SCHEMBL32668530

SCHEMBL32668530

O=C(c1ccc(F)cc1)N1CCC(O)(Cn2cnc3c(cnn3-c3ccc(F)c(N4CCOCC4)c3)c2=O)CC1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 19/20 0.58
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17870205 1.00 USP7 (0.58) USP7LMNASMN1; SMN2HSD17B10
SCHEMBL17869023 0.93 USP7 (0.58) USP7
SCHEMBL32668533 0.93 USP7 (0.58) USP7
SCHEMBL32668485 0.92 USP7 (0.58) USP7LMNASMN1; SMN2HSD17B10
SCHEMBL17869841 0.92 USP7 (0.58) USP7LMNASMN1; SMN2HSD17B10
SCHEMBL17869615 0.87 USP7 (0.62) USP7
SCHEMBL32668446 0.87 USP7 (0.62) USP7
SCHEMBL19888832 0.87 USP7 (0.71) USP7
SCHEMBL17869144 0.87 USP7 (0.59) USP7SMN1; SMN2
SCHEMBL17869801 0.86 USP7 (0.64) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed